Second Balkan Conference on Personalized Medicine: Program

personalised medicine

Second Balkan Conference on Personalized Medicine: Program

Second Balkan Conference on Personalized Medicine

REGISTER FOR THE EVENT

October 24th-25th, 2019, “Opal”Hall, Hotel “Ramada”, Sofia

Organized by the Bulgarian Alliance for Precision and Personalized Medicine – BAPPM

In collaboration with the European Alliance for Personalised Medicine – EAPM, Medical University Pleven and Bulgarian Society of Human Genetics and Genomics

Program

Thursday, October 24th, 2019

13.30 – 14.00 Registration

14.00 – 14.30 Opening: Setting the Scene

Dr. Jasmina Koeva, Chair of the Board, BAPPM

Denis Horgan, Executive Director EAPM

Keynote opening speech: Maria Gabriel – European Commissioner for Digital Economy and Society

Discussion with European Commissioner

14.30 – 16.00 First Plenary Session: Forward Together in the Personalised Medicine Era

Personalized Medicine – What will be covered in this opening session is the broad impact of the personalized medicine, which promises to create a new paradigm in healthcare.

The key is to find the optimum ways by which to integration personalized medicine into the EU’s healthcare systems, facilitate, the introduction of innovative pharmaceuticals and diagnostics, and build the necessary legal and regulatory frames.

In addition, there is a need to formulate optimal HTA of personalized medicine products, and, of course, bring about the best pathways to dramatically improve patient access to innovative treatments

Chair of session and Scene Setting: Denis Horgan, Executive Director EAPM

Karina Angelieva – Deputy Minister of Education and Science, Bulgaria:”Bulgaria on the European Map of Personalised Medicine – BBMRI, EATRIS, Centers of Excellence and Centres of Competence, National Research Programme” 

Dr. Tuula Helander – Finnish Presidency of European Council, Ministry of Social Affairs and Health, Finland

Ass. prof. dr. Lachezar Ivanov – Vice-chair of Health Commission in the Parliament of Bulgaria – invited

Dr. Jana Makedonska, Policy Officer, Unit for Health Innovations, DG Research & Innovation, European Commission: “European support for international cooperation in personalised medicine”

Q&A

16.00 – 17.40 Second Plenary Session:  Genomics for Healthcare

This session will look at new achievements in human genomics and genetics alongside gene therapy and the European Genomic Initiative “1+MG”.

With rising healthcare costs and systems being increasingly challenged, genomics has the potential to impact the health of all of us and provide diagnostic, economic and efficiency benefits, ensuring a patient has the right information, to get the right treatment, at the right time.

The potential for bettering the health of citizens across all Member States is huge.

If fully realized genomics will have a positive impact on the health of all of us by giving diagnostic, economic and efficiency benefits by ensuring the right patient, gets the right diagnosis and treatment, at the right time. Also hugely important for healthcare (and fiscal) reasons is the preventative sector which involves screening and early diagnosis, while the session will also include the important areas of rare diseases, oncology and neurological diseases.

Precision diagnostics are vital today, so we will look at NGS in preventive medicine and clinical practice. Comprehensive genomic profiling will also be discussed.

On top of this, the growing area of AI in personalized medicine cannot be denied, but implementing it is a key. Here we look at the current status and future possibilities.

Session chair: Prof. Dr. Draga Toncheva – President of Bulgarian Scientific Society for Human Genomics and Genetics

Setting the Scene: Dr. Jasmina Koeva-Balabanova, Chair of BAPPM: “1+ MG”Initiative

Prof. Dr. Borut Peterlin, Head of the Clinical Institute of Medical Genetics, Ljubljana, Slovenia:  Public health genomics: lessons from rare diseases”

Dr. Radoslav Mangaldjiev – Chair of Society of Medical Oncologists, Specialized Hospital for Active Treatment in Oncology, Sofia, Bulgaria: “The Advantage of Foundation Medicine-Comprehensive Genomic Profiling in clinical Practice”

 Hari Radhakrishnan, Chief Business Development Officer at NIPD Genetics, Cyprus: “Next-generation oncology panels for detailed analysis of cancer genes”

Prof. Dr. Draga Toncheva, President of Bulgarian Scientific Society for Human Genomics and Genetics: Medical genetic counseling and risk assessment for hereditary prostate cancer”

Q&A

17.40 – 18.00 Coffee-break

18.00 – 19.10 Third Plenary Session:  The pathology of Personalised Medicine

Molecular pathology – specifically new achievements and implementation in clinical practice.

Precision imaging in modern-day healthcare.

Session chair: Prof. dr. Savelina Popovska – Vice-rector Medical University Pleven, Bulgaria

Prof. Dr. George J Netto, Chair of Department of Clinical Pathology, University of Alabama at Birmingham, USA:  “Molecular Pathology – opportunities and challenges” 

Prof. Sven Seiwerth – Head of Department of Pathology, University of Zagreb, Croatia: Predictive biomarker testing in Croatia

Prof. Dr. Sonya Sergieva-Chief of Department “Nuclear Medicine”, Specialized Hospital in Active Treatment in Oncology, Sofia, Bulgaria:Teranostica –  current nuclear medicine diagnostic and therapeutic approach for personalized   treatment of neuroendocrine tumors

Q&A

19.30 – 22.00 Official Dinner and announcement of the winners of BAPPM Awards for Personalized Medicine in Bulgaria

Host: Dr. Jasmina Koeva-Balabanova, Chair of the Board of BAPPM

Friday, October 25th, 2019

08.30 – 09.0 Registration and Morning Coffee

09.00 – 12.00 Fourth Plenary Session: Personalized medicine in oncology 

This session will cover screening, targeted and combined therapy, as well as adjuvant and neoadjuvant therapy.

Also covered will be immunotherapy, radiotherapy, the monitoring of lung cancer, as well as breast cancer, colon cancer, prostate cancer, melanoma, pancreatic cancer, and head and neck cancer.

However, as always, we should be aware of the economic impacts (good and bad) of precision medicine. An outstanding high cost will not be sustainable in the long term, so development of technologies for cost reduction should not be ignored

Chair: Antoni Monserrat Moliner – Active Senior on Public Health for the European Commission

09.00-10.20 Guidelines and Best Practices

Ciaran Nicholl, Joint Research Center Ispra, European Commission: ”Evidence-based European Guidelines for quality assured, patient-centric cancer health care”

Beata Jagielska, Maria Sklodowska-Curie Memorial Cancer Center and Institute of Oncology; Department of Oncological Diagnostic, Cardio-Oncology and Palliative Care, Warsaw, Poland: “Value Based Healthcare as challenge for innovative medicine”

Dr. Rositza Krasteva – Head of Oncology Center/Comprehensive Cancer Care/ and Medical Oncology Department, “UniHospital”, Panayurishte, Bulgaria:”Personalised Cancer Therapy”

Q&A

10.20 – 10.40 Networking Break

10.40 – 12.00 Early Diagnosis and Screening – new technologies and personalization

Chair: Dr. Rositza Krasteva – Head of Oncology Center “UniHospital”,    Panayurishte, Bulgaria

Prof. Dr. George Momekov-Chairman of Bulgarian Scientific    Pharmaceutical Society, Bulgaria: ”Advanced Prostate Cancer – personalized approach”

Dr. Alexander Simidchiev-Chief of Department of Functional Diagnostics, Medical Institute of the Ministry of Interior, Bulgaria: ”A dose of screening – personalising prophylaxis

Prof. Dr. Sonya Sergieva-Chief of Department “Nuclear Medicine”, Specialized Hospital in Active Treatment in Oncology, Sofia, Bulgaria: ”Nuclear medicine methods for individualized diagnostics and therapy of thyroid cancer

Q&A

12.00-13.00 Working Lunch

13.00 – 14.50 Fifth Plenary Session: Personalized medicine and rare diseases, neurology and psychiatry

Some of the bottlenecks for precision medicine include the cost, as well as privacy concerns. These designer drugs are usually only effective for a small cohort of patients, so to recover costs put into developing the drug, a pharmaceutical company may charge much higher prices than for other medicines.

Also, like other health data, genetic information is private information, so security must be maintained for all patients.

For neurological diseases there is a need for comprehensive genetic assessment, classification, biomarkers, and treatments specified to a person’s molecular drivers.

This session will cover these topics and more.

Chair of session: Antoni Monserrat Moliner – Luxembourg National Committee for Rare Diseases

Setting the Scene:

Ciaran Nicholl, Joint Research Center Ispra, European Commission: ”New European Platform on Rare Disease Registration”

Expert Perspectives:

Prof. Dr. Rumen Stefanov – Director of “Institute for Rare Diseases”, Bulgaria: Challenges for improving access to innovative medicinal therapies”

Dr. Petja Stratieva – Development Executive Central and Eastern Europe “Retina International”: Equitable access to therapies for rare diseases: the patient perspective

Prof. Dr. Ara Garabed Kaprelyan – Head of Department of Neurology and  Neuroscience, Medical University Varna, Bulgaria:”Personalised Medicine and cutting-edge nanotechnologies in CNS diseases”

Ass. Prof. Dr. Diana Pendicheva – Medical University Pleven, Bulgaria:What’s new beyond Genome-Wide Association Studies in Pharmacogenomics of Affective Disorders?

Q&A

14.50 – 15.30 Sixth Plenary Session:  Cooperation & Balkan Framework

No Member State can go it alone when it comes to modern-day healthcare, despite the closely guarded national competence in this large arena.

Cross-border collaboration is vital now and will be even more so going forward, and the innovative work of regions must also be harnessed and, crucially, shared.

This final session will seek to establish the need for cooperation and seek a unity that such cooperation is necessary as we strive to make personalised medicine the norm, and deliver the right treatment to the right patient at the right time.

Chair of session: Jasmina Koeva-Balabanova, Chair of the Board, BAPPM, Bulgaria

Denis Horgan – Executive Director, EAPM

Representatives of participatory countries

Q&A

15.30 – 16.00 Poster Session

Chair of Session: Prof. Dr. George Christoff, Medical University Sofia, Bulgaria

16.00 – 16.15 Closing

Application for poster sessions: office.bappm@gmail.com

Official languages: Bulgarian and English

Лектори, потвърдили участие:

Maria Gabriel
European Commissioner for Digital Economy and Society

Dr. Tuula Helander
Finnish Presidency of European Council, Ministry of Social Affairs and Health, Secretary General, Finnish Cancer Institute

Jana Makedonska
RTD, European Commission, Policy and Research Program Officer – Health Research

Hari Radhakrishnan
Chief Business Development Officer at NIPD Genetics, Nicosia, Cyprus

Prof. Dr. Sonya Sergieva
Chief of Department “Nuclear Medicine”, Specialized Hospital in Active Treatment in Oncology, Sofia, Bulgaria

Prof. George Momekov
Chairman of Scientific Pharmeceutical Society, Bulgaria

Dr. Petja Stratieva
Development Executive Central and Eastern Europe “Retina International”

Dr. Jasmina Koeva-Balabanova
Chair of the Board, BAPPM

Prof. Dr. Draga Toncheva
President of Scientific Society of Human Genomics and Genetics, Bulgaria

Prof. Dr. Savelina Popovska
Vice-Rector, Medical University, Pleven, Bulgaria

Antoni Monserrat Moliner
Active Senior on Public Health for the European Commission, Member of the Luxembourg National Committee for Rare Diseases

Dr. Rositza Krasteva
Head of Oncology Center “Unihospital”/Comprehesive Cancer Care/ and Medical Oncology Department, Panagjurishte, Chairman of “Young Oncologist” Club, Bulgaria

Ass. Prof. Dr. Diana Pendicheva-Duhlenska
Medical University Pleven, Bulgaria

Denis Horgan
EAPM Executive Director

Prof. Dr. Borut Peterlin
Clinical Institute of Medical Genetics, University Medical Center, Ljubljana, Slovenia

Prof. Dr. George J Netto
Chairman of Department of Clinical Pathology, University of Alabama at Birminhgam, USA

Ciaran Nicholl
Joint Reseach Center, Ispra, European Commission

Dr. Alexander Simidchiev
Chief of Department of Functional Diagnostics, Medical Institute of the Ministry of Interior, Bulgaria

Prof. Dr. Ara Kaprelyan
Head of Department of Neurology and Neurosciense, Medical University Varna

Karina Angelieva
Deputy Minister of Education and Science, Bulgaria

Dr. Radoslav Mangaldjiev
Chair of Society of Medical Oncologists, Chief of Department of Medical Oncology, Specialized Hospital of Active Treatment in Oncology, Sofia, Bulgaria

Prof. Dr. Sven Seiwerth
Head of Institute of Pathology, Medical School, University of Zagreb, Croatia

Dr. Beata Jagielska
Deputy Director Scientific Institute of Oncology “Maria Sklodovska-Curie”, Warsaw, President of Polish Alliance for Personalised Medicine, Poland

Prof. Dr. Rumen Stefanov
Director of Institue of Rare Diseases, Bulgaria

Prof. dr. George Christoff
Faculty of Public Health, Medical University Sofia, Bulgaria

Thanks to the generous support of:

Silver sponsors:

Bronze sponsors:

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